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Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility
Escherichia coli endonuclease VIII (Nei) excises oxidized pyrimidines from DNA. It shares significant sequence homology and similar mechanism with Fpg, a bacterial 8-oxoguanine glycosylase. The structure of a covalent Nei–DNA complex has been recently determined, revealing critical amino acid residu...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1199562/ https://ncbi.nlm.nih.gov/pubmed/16145054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki796 |
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