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Efficient isothermal expansion of human telomeric and minisatellite repeats by Thermococcus litoralis DNA polymerase

Repeating DNA sequences, such as telomeres, centromeres, and micro- and mini-satellites, comprise 50% of the genome and play important roles in regulatory and pathogenic mechanisms. In order to study structures and functions of such repeating sequences, it is important to have simple and efficient m...

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Autors principals: Hartig, Jörg S., Kool, Eric T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199558/
https://ncbi.nlm.nih.gov/pubmed/16284196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki803
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