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A new method for determining the absolute molarity of solutions of trypsin and chymotrypsin by using p-nitrophenyl N(2)-acetyl-N(1)-benzylcarbazate

1. p-Nitrophenyl N(2)-acetyl-N(1)-benzylcarbazate (NPABC) was synthesized and shown to acylate α-chymotrypsin stoicheiometrically; reaction at 25° occurs almost instantaneously at pH7·04 and within 2min. at pH5·04 and there is no observable turnover during 10min. 2. The absolute molarity of solution...

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Autors principals: Elmore, D. T., Smyth, J. J.
Format: Artigo
Idioma:Inglês
Publicat: 1968
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1198616/
https://ncbi.nlm.nih.gov/pubmed/5642613
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