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Association between Maternal Age and Meiotic Recombination for Trisomy 21

Altered genetic recombination has been identified as the first molecular correlate of chromosome nondisjunction in both humans and model organisms. Little evidence has emerged to link maternal age—long recognized as the primary risk factor for nondisjunction—with altered recombination, although some...

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Hlavní autoři: Lamb, Neil E., Yu, Kai, Shaffer, John, Feingold, Eleanor, Sherman, Stephanie L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196437/
https://ncbi.nlm.nih.gov/pubmed/15551222
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