Safety, Tolerability, and Pharmacokinetics of Micafungin (FK463) in Febrile Neutropenic Pediatric Patients

Micafungin (FK463) is a new parenteral echinocandin. A multicenter, phase I, open-label, sequential-group dose escalation study was conducted to assess the safety, tolerability, and pharmacokinetics of micafungin in neutropenic pediatric patients. A total of 77 patients stratified by age (2 to 12 an...

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Detalhes bibliográficos
Main Authors: Seibel, Nita L., Schwartz, Cindy, Arrieta, Antonio, Flynn, Patricia, Shad, Aziza, Albano, Edith, Keirns, James, Lau, Wendi M., Facklam, David P., Buell, Donald N., Walsh, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196271/
https://ncbi.nlm.nih.gov/pubmed/16048942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3317-3324.2005
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