Efficacy of Cefepime and Imipenem in Experimental Murine Pneumonia Caused by Porin-Deficient Klebsiella pneumoniae Producing CMY-2 β-Lactamase

Previous studies have shown decreased in vitro activity of zwitterionic cephalosporins and carbapenems against porin-deficient Klebsiella pneumoniae expressing a plasmid-mediated AmpC-type β-lactamase (PACBL). The in vitro and in vivo activities of cefepime and imipenem were evaluated against the po...

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Autors principals: Pichardo, Cristina, Rodríguez-Martínez, José Manuel, Pachón-Ibañez, María E., Conejo, Carmen, Ibáñez-Martínez, José, Martínez-Martínez, Luis, Pachón, Jerónimo, Pascual, Álvaro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196264/
https://ncbi.nlm.nih.gov/pubmed/16048941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3311-3316.2005
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