Identification of Residues Responsible for the Defective Virulence Gene Regulator Mga Produced by a Natural Mutant of Streptococcus pyogenes

Mga is a transcriptional regulator in the pathogen Streptococcus pyogenes that positively activates several important virulence genes involved in colonization and immune evasion in the human host. A naturally occurring mutant of Mga that is defective in its ability to activate transcription has been...

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Bibliographic Details
Main Authors: Vahling, Cheryl M., McIver, Kevin S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Molecular Biology of Pathogens
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196160/
https://ncbi.nlm.nih.gov/pubmed/16109937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.17.5955-5966.2005
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