Nevirapine Plasma Exposure Affects both Durability of Viral Suppression and Selection of Nevirapine Primary Resistance Mutations in a Clinical Setting

The relationship between nevirapine plasma concentrations and the durability of both viral suppression (VS) and selection of nevirapine primary resistance mutations (PRMs) was evaluated. A nevirapine trough concentration (C(trough)) of >4,300 ng/ml was found to predict longer VS. Patients with ne...

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Autors principals: González de Requena, D., Bonora, S., Garazzino, S., Sciandra, M., D'Avolio, A., Raiteri, R., Marrone, R., Boffito, M., De Rosa, F. G., Sinicco, A., Di Perri, G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1195440/
https://ncbi.nlm.nih.gov/pubmed/16127084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3966-3969.2005
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