Variation in IL-1β gene expression is a major determinant of genetic differences in arthritis aggressivity in mice

In humans and in animal models, susceptibility to arthritis is under complex genetic control, reflecting influences on the immunological processes that initiate autoimmunity and on subsequent inflammatory mechanisms in the joints. The effector phases are conveniently modeled by the K/BxN serum trans...

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Autors principals: Ohmura, Koichiro, Johnsen, Alyssa, Ortiz-Lopez, Adriana, Desany, Paul, Roy, Matt, Besse, Whitney, Rogus, John, Bogue, Molly, Puech, Anne, Lathrop, Mark, Mathis, Diane, Benoist, Christophe
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194932/
https://ncbi.nlm.nih.gov/pubmed/16113081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504325102
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