Variation in IL-1β gene expression is a major determinant of genetic differences in arthritis aggressivity in mice

In humans and in animal models, susceptibility to arthritis is under complex genetic control, reflecting influences on the immunological processes that initiate autoimmunity and on subsequent inflammatory mechanisms in the joints. The effector phases are conveniently modeled by the K/BxN serum trans...

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Bibliografiske detaljer
Main Authors: Ohmura, Koichiro, Johnsen, Alyssa, Ortiz-Lopez, Adriana, Desany, Paul, Roy, Matt, Besse, Whitney, Rogus, John, Bogue, Molly, Puech, Anne, Lathrop, Mark, Mathis, Diane, Benoist, Christophe
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194932/
https://ncbi.nlm.nih.gov/pubmed/16113081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504325102
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