Variation in IL-1β gene expression is a major determinant of genetic differences in arthritis aggressivity in mice

In humans and in animal models, susceptibility to arthritis is under complex genetic control, reflecting influences on the immunological processes that initiate autoimmunity and on subsequent inflammatory mechanisms in the joints. The effector phases are conveniently modeled by the K/BxN serum trans...

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Detalhes bibliográficos
Main Authors: Ohmura, Koichiro, Johnsen, Alyssa, Ortiz-Lopez, Adriana, Desany, Paul, Roy, Matt, Besse, Whitney, Rogus, John, Bogue, Molly, Puech, Anne, Lathrop, Mark, Mathis, Diane, Benoist, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194932/
https://ncbi.nlm.nih.gov/pubmed/16113081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504325102
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