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Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization

Glycosylated natural products are reliable platforms for the development of many front-line drugs, yet our understanding of the relationship between attached sugars and biological activity is limited by the availability of convenient glycosylation methods. When a universal chemical glycosylation met...

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Bibliographic Details
Main Authors: Langenhan, Joseph M., Peters, Noël R., Guzei, Ilia A., Hoffmann, F. Michael, Thorson, Jon S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194917/
https://ncbi.nlm.nih.gov/pubmed/16105948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503270102
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