Importin 7 May Be Dispensable for Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus Infection of Primary Macrophages

In an in vitro assay employing reconstituted nuclei, importin 7 (IPO7) has been implicated in nuclear translocation of human immunodeficiency virus type 1 (HIV-1) cDNA. Using RNA interference technology, we inhibited expression of IPO7 by 80 to 95% in primary macrophages and in HeLa cells and monito...

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Bibliographic Details
Main Authors: Zielske, Steven P., Stevenson, Mario
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193637/
https://ncbi.nlm.nih.gov/pubmed/16103209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11541-11546.2005
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