The Secreted Form of Dengue Virus Nonstructural Protein NS1 Is Endocytosed by Hepatocytes and Accumulates in Late Endosomes: Implications for Viral Infectivity

The flavivirus nonstructural protein NS1 is expressed as three discrete species in infected mammalian cells: an intracellular, membrane-associated form essential for viral replication, a cell surface-associated form that may be involved in signal transduction, and a secreted form (sNS1), the biologi...

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Bibliographic Details
Main Authors: Alcon-LePoder, Sophie, Drouet, Marie-Thérèse, Roux, Pascal, Frenkiel, Marie-Pascale, Arborio, Michel, Durand-Schneider, Anne-Marie, Maurice, Michèle, Le Blanc, Isabelle, Gruenberg, Jean, Flamand, Marie
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193635/
https://ncbi.nlm.nih.gov/pubmed/16103191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11403-11411.2005
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