Multiple Gene Segments Control the Temperature Sensitivity and Attenuation Phenotypes of ca B/Ann Arbor/1/66

Cold-adapted (ca) B/Ann Arbor/1/66 is the influenza B virus strain master donor virus for FluMist, a live, attenuated, influenza virus vaccine licensed in 2003 in the United States. Each FluMist vaccine strain contains six gene segments of the master donor virus; these master donor gene segments con...

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Detalhes bibliográficos
Main Authors: Hoffmann, Erich, Mahmood, Kutubuddin, Chen, Zhongying, Yang, Chin-Fen, Spaete, Joshua, Greenberg, Harry B., Herlocher, M. Louise, Jin, Hong, Kemble, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193632/
https://ncbi.nlm.nih.gov/pubmed/16103152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11014-11021.2005
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