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Broad Cross-Clade T-Cell Responses to Gag in Individuals Infected with Human Immunodeficiency Virus Type 1 Non-B Clades (A to G): Importance of HLA Anchor Residue Conservation

We aimed to identify cross-clade human immunodeficiency virus type 1 (HIV-1) specific T-cell responses among 10 HLA-typed individuals who were infected with non-B HIV-1 strains (A, AG, C, D, G, or F) and to correlate these responses with genetic variation in documented T-cell epitopes. T-cell reacti...

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Detalhes bibliográficos
Main Authors: Geels, Mark J., Dubey, Sheri A., Anderson, Kiersten, Baan, Elly, Bakker, Margreet, Pollakis, Georgios, Paxton, William A., Shiver, John W., Goudsmit, Jaap
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193573/
https://ncbi.nlm.nih.gov/pubmed/16103177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11247-11258.2005
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