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Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing

Studies of expressed sequence tag data sets have revealed large numbers of splicing variants for human genes, but it remains challenging to distinguish functionally important variants from aberrant splicing, clarify the nature of the alternative functions, and understand the signals that regulate sp...

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Autori principali: Baek, Daehyun, Green, Phil
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1192826/
https://ncbi.nlm.nih.gov/pubmed/16123126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506139102
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