A model of the ternary complex of interleukin-10 with its soluble receptors

BACKGROUND: Interleukin-10 (IL-10) is a cytokine whose main biological function is to suppress the immune response by induction of a signal(s) leading to inhibition of synthesis of a number of cytokines and their cellular receptors. Signal transduction is initiated upon formation of a ternary comple...

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Bibliographic Details
Main Authors: Pletnev, Sergei, Magracheva, Eugenia, Wlodawer, Alexander, Zdanov, Alexander
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1192808/
https://ncbi.nlm.nih.gov/pubmed/15985167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-5-10
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