Pancreatic carcinoma cell killing via adenoviral mediated delivery of the herpes simplex virus thymidine kinase gene.

OBJECTIVE: Use of adenoviral mediated delivery of the herpes simplex virus thymidine kinase (HSV-TK) gene as a gene therapy strategy for carcinoma of the pancreas. SUMMARY BACKGROUND DATA: Expression of HSV-TK selectively sensitizes cells to the nucleoside analog ganciclovir (GCV). This strategy has...

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Main Authors: Rosenfeld, M E, Vickers, S M, Raben, D, Wang, M, Sampson, L, Feng, M, Jaffee, E, Curiel, D T
格式: Artigo
語言:Inglês
出版: 1997
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190805/
https://ncbi.nlm.nih.gov/pubmed/9193188
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