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Type 2 iodothyronine deiodinase is the major source of plasma T(3) in euthyroid humans
The relative roles of the types 1 and 2 iodothyronine deiodinases (D1 and D2) in extrathyroidal 3,5,3′-triiodothyronine (T(3)) production in humans are unknown. We calculated the rate of thyroxine (T(4)) to T(3) conversion by intact cells transiently expressing D1 or D2 at low (2 pM), normal (20 pM)...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1190373/ https://ncbi.nlm.nih.gov/pubmed/16127464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25083 |
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