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Type 2 iodothyronine deiodinase is the major source of plasma T(3) in euthyroid humans

The relative roles of the types 1 and 2 iodothyronine deiodinases (D1 and D2) in extrathyroidal 3,5,3′-triiodothyronine (T(3)) production in humans are unknown. We calculated the rate of thyroxine (T(4)) to T(3) conversion by intact cells transiently expressing D1 or D2 at low (2 pM), normal (20 pM)...

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Bibliografische gegevens
Hoofdauteurs: Maia, Ana Luiza, Kim, Brian W., Huang, Stephen A., Harney, John W., Larsen, P. Reed
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190373/
https://ncbi.nlm.nih.gov/pubmed/16127464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25083
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