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Type 2 iodothyronine deiodinase is the major source of plasma T(3) in euthyroid humans

The relative roles of the types 1 and 2 iodothyronine deiodinases (D1 and D2) in extrathyroidal 3,5,3′-triiodothyronine (T(3)) production in humans are unknown. We calculated the rate of thyroxine (T(4)) to T(3) conversion by intact cells transiently expressing D1 or D2 at low (2 pM), normal (20 pM)...

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Detalles Bibliográficos
Autores principales: Maia, Ana Luiza, Kim, Brian W., Huang, Stephen A., Harney, John W., Larsen, P. Reed
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190373/
https://ncbi.nlm.nih.gov/pubmed/16127464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25083
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