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hMOF Histone Acetyltransferase Is Required for Histone H4 Lysine 16 Acetylation in Mammalian Cells

Reversible histone acetylation plays an important role in regulation of chromatin structure and function. Here, we report that the human orthologue of Drosophila melanogaster MOF, hMOF, is a histone H4 lysine K16-specific acetyltransferase. hMOF is also required for this modification in mammalian ce...

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Main Authors: Taipale, Mikko, Rea, Stephen, Richter, Karsten, Vilar, Ana, Lichter, Peter, Imhof, Axel, Akhtar, Asifa
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190338/
https://ncbi.nlm.nih.gov/pubmed/16024812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6798-6810.2005
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