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hMOF Histone Acetyltransferase Is Required for Histone H4 Lysine 16 Acetylation in Mammalian Cells

Reversible histone acetylation plays an important role in regulation of chromatin structure and function. Here, we report that the human orthologue of Drosophila melanogaster MOF, hMOF, is a histone H4 lysine K16-specific acetyltransferase. hMOF is also required for this modification in mammalian ce...

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Autors principals: Taipale, Mikko, Rea, Stephen, Richter, Karsten, Vilar, Ana, Lichter, Peter, Imhof, Axel, Akhtar, Asifa
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190338/
https://ncbi.nlm.nih.gov/pubmed/16024812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6798-6810.2005
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