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hMOF Histone Acetyltransferase Is Required for Histone H4 Lysine 16 Acetylation in Mammalian Cells

Reversible histone acetylation plays an important role in regulation of chromatin structure and function. Here, we report that the human orthologue of Drosophila melanogaster MOF, hMOF, is a histone H4 lysine K16-specific acetyltransferase. hMOF is also required for this modification in mammalian ce...

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Bibliografiske detaljer
Main Authors: Taipale, Mikko, Rea, Stephen, Richter, Karsten, Vilar, Ana, Lichter, Peter, Imhof, Axel, Akhtar, Asifa
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190338/
https://ncbi.nlm.nih.gov/pubmed/16024812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6798-6810.2005
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