hMOF Histone Acetyltransferase Is Required for Histone H4 Lysine 16 Acetylation in Mammalian Cells

Reversible histone acetylation plays an important role in regulation of chromatin structure and function. Here, we report that the human orthologue of Drosophila melanogaster MOF, hMOF, is a histone H4 lysine K16-specific acetyltransferase. hMOF is also required for this modification in mammalian ce...

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Bibliographic Details
Main Authors: Taipale, Mikko, Rea, Stephen, Richter, Karsten, Vilar, Ana, Lichter, Peter, Imhof, Axel, Akhtar, Asifa
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Chromosome Structure and Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190338/
https://ncbi.nlm.nih.gov/pubmed/16024812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6798-6810.2005
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