Death Receptor-Induced Signaling Pathways Are Differentially Regulated by Gamma Interferon Upstream of Caspase 8 Processing

FasL and gamma interferon (IFN-γ) are produced by activated T cells and NK cells and synergistically induce apoptosis. Although both cytokines can also elicit proinflammatory responses, a possible cross talk of these ligands with respect to nonapoptotic signaling has been poorly addressed. Here, we...

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Bibliografiska uppgifter
Huvudupphovsmän: Siegmund, Daniela, Wicovsky, Andreas, Schmitz, Ingo, Schulze-Osthoff, Klaus, Kreuz, Sebastian, Leverkus, Martin, Dittrich-Breiholz, Oliver, Kracht, Michael, Wajant, Harald
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2005
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190324/
https://ncbi.nlm.nih.gov/pubmed/16024776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6363-6379.2005
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