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ATPase/Helicase Activities of p68 RNA Helicase Are Required for Pre-mRNA Splicing but Not for Assembly of the Spliceosome

We have previously demonstrated that p68 RNA helicase, as an essential human splicing factor, acts at the U1 snRNA and 5′ splice site (5′ss) duplex in the pre-mRNA splicing process. To further analyze the function of p68 in the spliceosome, we generated two p68 mutants (motif V, RGLD to LGLD, and mo...

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Detaylı Bibliyografya
Asıl Yazarlar: Lin, Chunru, Yang, Liuqing, Yang, Jenny J., Huang, Youliang, Liu, Zhi-Ren
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190289/
https://ncbi.nlm.nih.gov/pubmed/16107697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7484-7493.2005
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