Dual Functions of the Steroid Hormone Receptor Coactivator 3 in Modulating Resistance to Thyroid Hormone

Mutations of the thyroid hormone receptor β (TRβ) gene cause resistance to thyroid hormone (RTH). RTH is characterized by increased serum thyroid hormone associated with nonsuppressible thyroid-stimulating hormone (TSH) and impaired growth. It is unclear how the actions of TRβ mutants are modulated...

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Autors principals: Ying, Hao, Furuya, Fumihiko, Willingham, Mark C., Xu, Jianming, O'Malley, Bert W., Cheng, Sheue-yann
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190271/
https://ncbi.nlm.nih.gov/pubmed/16107715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7687-7695.2005
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