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Identification of Splicing Silencers and Enhancers in Sense Alus: a Role for Pseudoacceptors in Splice Site Repression

Auxiliary splicing signals in introns play an important role in splice site selection, but these elements are poorly understood. We show that a subset of serine/arginine (SR)-rich proteins activate a cryptic 3′ splice site in a sense Alu repeat located in intron 4 of the human LST1 gene. Utilization...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lei, Haixin, Vořechovský, Igor
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190243/
https://ncbi.nlm.nih.gov/pubmed/16055705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.6912-6920.2005
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