Increased Vascular Smooth Muscle Contractility in TRPC6(−)(/)(−) Mice

Among the TRPC subfamily of TRP (classical transient receptor potential) channels, TRPC3, -6, and -7 are gated by signal transduction pathways that activate C-type phospholipases as well as by direct exposure to diacylglycerols. Since TRPC6 is highly expressed in pulmonary and vascular smooth muscle...

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Bibliographic Details
Main Authors: Dietrich, Alexander, Mederos y Schnitzler, Michael, Gollasch, Maik, Gross, Volkmar, Storch, Ursula, Dubrovska, Galyna, Obst, Michael, Yildirim, Eda, Salanova, Birgit, Kalwa, Hermann, Essin, Kirill, Pinkenburg, Olaf, Luft, Friedrich C., Gudermann, Thomas, Birnbaumer, Lutz
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190236/
https://ncbi.nlm.nih.gov/pubmed/16055711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.6980-6989.2005
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