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HIF1-alpha overexpression indicates a good prognosis in early stage squamous cell carcinomas of the oral floor

BACKGROUND: Hypoxia-inducible factor 1 (HIF-1) is a transcription factor, which plays a central role in biologic processes under hypoxic conditions, especially concerning tumour angiogenesis. HIF-1α is the relevant, oxygen-dependent subunit and its overexpression has been associated with a poor prog...

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Main Authors: Fillies, Thomas, Werkmeister, Richard, van Diest, Paul J, Brandt, Burkhard, Joos, Ulrich, Buerger, Horst
格式: Artigo
語言:Inglês
出版: BioMed Central 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190162/
https://ncbi.nlm.nih.gov/pubmed/16035955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-84
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