Weak HIF-1alpha expression indicates poor prognosis in resectable pancreatic ductal adenocarcinoma

BACKGROUND: HIF-1alpha and CAIX proteins are commonly expressed under hypoxic conditions, but other regulatory factors have been described as well. Pancreatic ductal adenocarcinoma (PDAC) is characterized by hypoxia and strong stromal reaction and has a dismal prognosis with the currently available...

Full description

Saved in:
Bibliographic Details
Published in:World J Surg Oncol
Main Authors: Leppänen, Joni, Helminen, Olli, Huhta, Heikki, Kauppila, Joonas H., Isohookana, Joel, Haapasaari, Kirsi-Maria, Parkkila, Seppo, Saarnio, Juha, Lehenkari, Petri P., Karttunen, Tuomo J.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033289/
https://ncbi.nlm.nih.gov/pubmed/29973215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-018-1432-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items