Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death

Transient global or forebrain ischemia induced experimentally in animals can cause selective, delayed neuronal death of hippocampal CA1 pyramidal neurons. A striking feature is a delayed rise in intracellular free Zn(2+) in CA1 neurons just before the onset of histologically detectable cell death. H...

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Autors principals: Noh, Kyung-Min, Yokota, Hidenori, Mashiko, Toshihiro, Castillo, Pablo E., Zukin, R. Suzanne, Bennett, Michael V. L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189338/
https://ncbi.nlm.nih.gov/pubmed/16093311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505408102
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