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Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: Role in apical retention and targeting

Proximal tubular reabsorption of filtered sodium by the sodium/hydrogen exchanger isoform 3 (NHE3), located on the apical membrane, is fundamental to the maintenance of systemic volume and pH homeostasis. NHE3 is finely regulated by a variety of hormones and by changes in ionic composition and volum...

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Autores principales: Alexander, R. Todd, Furuya, Wendy, Szászi, Katalin, Orlowski, John, Grinstein, Sergio
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189301/
https://ncbi.nlm.nih.gov/pubmed/16103375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409197102
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