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Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
Severe acute respiratory syndrome (SARS) is caused by an emergent coronavirus (SARS-CoV), for which there is currently no effective treatment. SARS-CoV mediates receptor binding and entry by its spike (S) glycoprotein, and infection is sensitive to lysosomotropic agents that perturb endosomal pH. We...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1188015/ https://ncbi.nlm.nih.gov/pubmed/16081529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505577102 |
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