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Molecular basis of alanine discrimination in editing site

AlaX is the homologue of the class II alanyl-tRNA synthetase editing domain and has been shown to exhibit autonomous editing activity against mischarged tRNA(Ala). Here, we present the structures of AlaX from the archaeon Pyrococcus horikoshii in apo form, complexed with zinc, and with noncognate am...

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Hlavní autoři: Sokabe, Masaaki, Okada, Ayuko, Yao, Min, Nakashima, Takashi, Tanaka, Isao
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187966/
https://ncbi.nlm.nih.gov/pubmed/16087889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502119102
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