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Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates rather than resolves established inflammation

BACKGROUND: Fas receptor-mediated eosinophil apoptosis is currently forwarded as a mechanism resolving asthma-like inflammation. This view is based on observations in vitro and in airway lumen with unknown translatability to airway tissues in vivo. In fact, apoptotic eosinophils have not been detect...

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Hlavní autoři: Uller, Lena, Rydell-Törmänen, Kristina, Persson, Carl GA, Erjefält, Jonas S
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187926/
https://ncbi.nlm.nih.gov/pubmed/16086832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-90
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