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Structure and species as factors affecting the metabolism of some methoxy-6-sulphanilamidopyrimidines
1. A comparative study was made in man, rhesus monkey, rat and rabbit of the urinary excretion of 2-, 4- and 5-methoxy- and 2,4-, 2,5- and 4,5-dimethoxy-6-sulphanilamidopyrimidines given orally. 2. In the rabbit, 70–80% of the dose of each drug was excreted in 2 days, mainly as N(4)-acetyl derivativ...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1969
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1187803/ https://ncbi.nlm.nih.gov/pubmed/4974220 |
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