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Species differences in the metabolism of sulphadimethoxine

1. The fate of sulphadimethoxine (2,4-dimethoxy-6-sulphanilamidopyrimidine) was studied in man, rhesus monkey, dog, rat, guinea pig and rabbit. 2. About 20–46% of the dose (0·1g./kg.) of the drug is excreted in the urine in 24hr. in these species, except the rat, in which only 13% is excreted. 3. In...

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Bibliografiset tiedot
Päätekijät: Bridges, J. W., Kibby, M. R., Walker, S. R., Williams, R. T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1968
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187037/
https://ncbi.nlm.nih.gov/pubmed/4972257
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