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Study of the methylation and lack of deamination of deoxyribonucleic acid by N-methyl-N′-nitro-N-nitrosoguanidine

1. DNA labelled with (14)C in the purine residues was prepared by treating newborn rats with [(14)C]formate and killing them for preparation of nucleic acids at 11–17 months. This DNA was incubated with N-methyl-N′-nitro-N-nitrosoguanidine, and then analysed for products of methylation and deaminati...

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Bibliographic Details
Main Author: Craddock, Valda M.
Format: Artigo
Language:Inglês
Published: 1969
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187589/
https://ncbi.nlm.nih.gov/pubmed/5783466
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