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Thymidylate synthase protein expression and activity are related to the cell proliferation rate in human cancer cell lines

Aims: To ascertain whether the expression and enzyme activity of thymidylate synthase (TS) are related to the rapidity of cell proliferation in human cancer cell lines. Methods: Ten asynchronously growing human cancer cell lines of different origin were used, characterised by various doubling times....

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Bibliografiske detaljer
Main Authors: Derenzini, M, Montanaro, L, Treré, D, Chillà, A, Tazzari, P L, Dall’Olio, F, Öfner, D
Format: Artigo
Sprog:Inglês
Udgivet: British Medical Journal Publishing Group 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187262/
https://ncbi.nlm.nih.gov/pubmed/12354935
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