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The Sd(a) Synthase B4GALNT2 Reduces Malignancy and Stemness in Colon Cancer Cell Lines Independently of Sialyl Lewis X Inhibition
Background: The Sd(a) antigen and its biosynthetic enzyme B4GALNT2 are highly expressed in healthy colon but undergo a variable down-regulation in colon cancer. The biosynthesis of the malignancy-associated sialyl Lewis x (sLe(x)) antigen in normal and cancerous colon is mediated by fucosyltransfera...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7555213/ https://ncbi.nlm.nih.gov/pubmed/32911675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186558 |
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