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The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblasts

Although the role of transforming growth factor β (TGFβ) in initiating fibrosis is well established, the role that TGFβ plays in maintaining fibrosis is unclear. The gene encoding connective tissue growth factor (ccn2; ctgf), which promotes fibrosis, is not normally expressed in dermal fibroblasts u...

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Autors principals: Leask, A, Sa, S, Holmes, A, Shiwen, X, Black, C M, Abraham, D J
Format: Artigo
Idioma:Inglês
Publicat: British Medical Journal Publishing Group 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187059/
https://ncbi.nlm.nih.gov/pubmed/11376132
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