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Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effects

In MCF-7 breast cancer cells, the insulin-like growth factor 1 receptor (IGF-1R) and the oestrogen receptor (ER) are coexpressed and the two signalling systems are engaged in a crosstalk that results in synergistic growth. However, coupling between the signalling cascades is poorly understood. Oestr...

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Detalhes bibliográficos
Main Authors: Dupont, J, Le Roith, D
Formato: Artigo
Idioma:Inglês
Publicado em: British Medical Journal Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187053/
https://ncbi.nlm.nih.gov/pubmed/11376126
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