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Metabolism of megestrol acetate by rat adrenal glands in vitro

Megestrol acetate is metabolized by homogenates of rat adrenal glands to three more polar metabolites Y(2), Y(3) and Y(4). Their structures were investigated by microchemical reactions, paper chromatography, and ultraviolet and infrared spectroscopy. Metabolite Y(3) was identified as 17α-acetoxy-11β...

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Detalhes bibliográficos
Main Authors: Cooke, B. A., Vallance, D. K.
Formato: Artigo
Idioma:Inglês
Publicado em: 1968
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186760/
https://ncbi.nlm.nih.gov/pubmed/5669841
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