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Formation of an unstable covalent intermediate during the inhibition of electric-eel acetylcholinesterase with 1,3,2-dioxaphosphorinane 2-oxides.

The kinetics of interaction of eel acetylcholinesterase (EC 3.1.1.7) with 1,3,2-dioxaphosphorinane 2-oxides were investigated. It was demonstrated that the rate of spontaneous re-activation as well as the re-activation profile in the presence of 2-pyridine aldoxime methiodide of the inhibited enzyme...

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Bibliografske podrobnosti
Main Authors: Ashani, Y, Leader, H
Format: Artigo
Jezik:Inglês
Izdano: 1979
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186441/
https://ncbi.nlm.nih.gov/pubmed/444203
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