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Inhibition of acetylcholinesterase by derivatives of 1,3,2-dioxaphosphorinane 2-oxide.

Cholinesterases are inhibited by 2-fluoro-1,3,2-dioxaphosphorinane 2-oxide by a mechanism that involves a slow association step followed by a very slow phosphorylation step. No phosphorylation step was observed for the interaction between acetylcholinesterase and 2-S-[2'-(NN-diethylamino)ethyl]...

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Bibliographic Details
Main Author: Coult, D B
Format: Artigo
Language:Inglês
Published: 1976
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1172899/
https://ncbi.nlm.nih.gov/pubmed/949333
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