Calcium ions and the regulation of NAD+-linked isocitrate dehydrogenase from the mitochondria of rat heart and other tissues.

The effects of Ca2+ on the activity of isocitrate dehydrogenase (NAD+) in extracts of rat heart mitochondria were explored in the presence of MgCl2 by using EGTA buffers. In the absence of ADP, Ca2+ (about 30 micrometer) resulted in a slight increase in apparent Km for threo-Ds-isocitrate; in the pr...

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Bibliografske podrobnosti
Main Authors: Denton, R M, Richards, D A, Chin, J G
Format: Artigo
Jezik:Inglês
Izdano: 1978
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186314/
https://ncbi.nlm.nih.gov/pubmed/218557
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