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The Isy1p component of the NineTeen Complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing

Prp16p is a DEAH-box ATPase that transiently associates with the spliceosome to promote the structural transition required for the second chemical step. Yeast strains carrying the cold-sensitive allele prp16-302 stall the release of Prp16p at low temperatures, yet splice precursors with aberrant bra...

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Detalhes bibliográficos
Main Authors: Villa, Tommaso, Guthrie, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186189/
https://ncbi.nlm.nih.gov/pubmed/16103217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1336305
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