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The adenylate cyclase-activating activity of cholera toxin is not associated with a nicotinamide--adenine dinucleotide glycohydrolase activity.

The NAD+ glycohydrolase activity of cholera-toxin samples can be separated from their adenylate cyclase-activating activity by polyacrylamide-gel electrophoresis and is inhibited by sodium dodecyl sulphate (which does not inhibit the action of toxin on cells), but not by antibodies to pure toxin. It...

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Bibliographic Details
Main Authors: Tait, R M, van Heyningen, S
Format: Artigo
Language:Inglês
Published: 1978
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186012/
https://ncbi.nlm.nih.gov/pubmed/215119
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